Consideration of use of neuraminidase inhibitors such as oseltamivir and zanamivir in IgA nephropathy

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Synthetic approaches to the neuraminidase inhibitors zanamivir (Relenza) and oseltamivir phosphate (Tamiflu) for the treatment of influenza.

Influenza, a severe viral infection of the respiratory system, is responsible for a significant morbidity and mortality due to both annual epidemics and unpredictable pandemics. In the United States alone, 10-20% of the population is affected every year, which results in approximately 110,000 hospitalizations and more than 20,000 deaths with an estimated cost of U.S. $12 billion.1 In addition t...

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Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir.

The influenza virus neuraminidase (NA) inhibitors zanamivir and oseltamivir were introduced into clinical practice in various parts of the world between 1999 and 2002. In order to monitor the potential development of resistance, the Neuraminidase Inhibitor Susceptibility Network was established to coordinate testing of clinical isolates collected through the World Health Organization influenza ...

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Effect of oseltamivir, zanamivir or oseltamivir-zanamivir combination treatments on transmission of influenza in households.

BACKGROUND The effectiveness of neuraminidase inhibitors to reduce transmission when used as treatment in influenza-infected patients remains debated. METHODS In a prespecified analysis of a blinded randomized controlled trial on the efficacy of oseltamivir-zanamivir combination therapy versus oseltamivir and zanamivir monotherapy conducted during the 2008-2009 seasonal influenza epidemic, we...

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exploring interconnections between iranian efl teachers beleifs about the status of english as an international language (efl), use of mother tongue in efl classroom, and diffrences between native and non-native teachers of english

in one pole of the continuum of language learning, theoreticians and practitioners traditionally consider english as english as a second language or english as a foreign language. however, in the other pole of this continuum where english is thought of as the most effective tool for international communication, it is referred to as a lingua franca. those who favor an approach to english growing...

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ژورنال

عنوان ژورنال: Kidney International

سال: 2005

ISSN: 0085-2538

DOI: 10.1111/j.1523-1755.2005.00583_7.x